The LARIAT procedure is a percutaneous approach to immediate and complete left atrial appendage (LAA) closure without the need to leave an implant inside of the heart. Using an innovative approach to remote suture delivery, the LARIAT is precisely placed around the base of the LAA through a 13F SofTIP guide cannula using standard imaging techniques. There is no grasping or manipulation of the fragile LAA tissue and the closure location may be optimized with the ability to re-open the LARIAT snare as often as needed without deployment of the suture.